20 Best Anime series like Rin: Daughters of Mnemosyne (2008)

When Kouichi Sasakibara transfers to his new school, he can sense something frightening in the atmosphere of his new class, a secret none of them will talk about. At the center is the beautiful girl Mei Misaki. Kouichi is immediately drawn to her mysterious aura, but then he begins to realize that no one else in the class is aware of her presence.

Shinichi Izumi is a normal high school boy whose right hand has become infected with an alien parasite that names itself "Migi" ("right"). Migi is the first parasite to develop a symbiotic relationship with its host, as he and Shinichi slowly develop a grudging friendship. Migi isn't the only Parasite on earth, however, and as cases of Parasites killing humans begin to emerge, humans seek to kill off Parasites. Shinichi and Migi find themselves caught in between these two sides of the struggle over planet earth.

The one adored as the mother is not the real parent. The people living here together are not actual siblings. The Gracefield House is where orphaned children live. An irreplaceable home where 38 siblings and Mom live happy lives, even with no blood relations. However, their everyday life suddenly came to an abrupt end one day...

15 years ago, an unknown hyperspace gate opened over the Pacific. Beyond this gate lies Reto Semaani, a strange alternate world where fairies and monsters live.San Teresa City—a city where over two million immigrants live from both worlds. As a result, there are the haves and the have-nots. Here is the world's newest "city of dreams." But in the shadow of the chaos, crime is rampant: drugs, prostitution, and weapon trafficking. The detectives who stand up to these heinous crimes are in the San Teresa City Police. When the detective Kei Matoba and the alternate-world knight Tirana—two individuals who differ in gender, personality, and even world of origin—meet, an incident erupts. Two worlds. Two justices. From this, the curtain rises on a buddy police action story!

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The "paranormal science" story follows nine idiosyncratic individuals, linked by the "Choujou Kagaku Kirikiri Basara" occult summary blog run by 17-year-old second-year high school student Yuuta Gamon. Little incongruities that occur around these nine eventually lead to a larger, unimaginable event that may alter what is considered common sense in this world.

After losing their mother to a demon, two brothers grow up fighting supernatural beings.

There is an urban legend that tells of a shinigami that can release people from the pain they are suffering. This "Angel of Death" has a name—Boogiepop. And the legends are true. Boogiepop is real. When a rash of disappearances involving female students breaks out at Shinyo Academy, the police and faculty assume they just have a bunch of runaways on their hands. Yet some students know better. Something mysterious and foul is afoot. Is it Boogiepop or something even more sinister...?

Legendary half-vampire, half-human vampire hunter Blade is tracking Deacon Frost, a very powerful and influential vampire who killed his mother and who heads Existence, a secretive vampire organization that operates in Southeast Asia.

With a maintenance robot and a deadly fugitive tagging along, friendship droid S.A.M searches for its best friend, the heir to a kingdom under siege.

In the near future, most of mankind now lives in a handful of city states. There, for the privileged elite, life should be perfect. But for young Sion, life has become a nightmare since letting a strange boy spend the night in his apartment. Banished to the outskirts of the city, Sion now finds himself in worse danger as his inquiry into a new series of mysterious deaths results in his being arrested on suspicion of murder! Now, on the run, the two young men have only one chance at survival.

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High schooler Yūta Iridatsu has experienced “astral projection” i.e. his spirit has been separated from his body. He woke up in a mansion named Koraikan and met a cat spirit named Chiranosuke, who told him “You must find the Sacred Tome of Koraikan in order to return to your physical body.” While searching through corridors of Koraikan, Yūta bumped into underpants of its female residents, and doing so would, eh, create some big trouble for planet Earth.

In a world powered by advanced technology, crime and action unfold in the archipelagic nation of Cremona. Genius investigator Keith Flick rejoins the royal police force just as serial killer "B" emerges. Mysterious youth Koku may be an ally, or a target.

Sakaido is a genius detective who can track down any criminal. But when his daughter is murdered, revenge lands him on the other side of the law. Now in prison, he helps the police solve mysteries using a system that invades a person’s identity. Little by little, a trail of blood forms, and it all leads back to his daughter’s murderer.

Tomie Kawakami is a femme fatale with long black hair and a beauty mark just under her left eye. She can seduce nearly any man, and drive them to murder as well, even though the victim is often Tomie herself. While one lover seeks to keep her for himself, another grows terrified of the immortal succubus. But soon they realize no matter how many times they kill her, the world will never be free of Tomie.

Many centuries ago, man's Armageddon gave birth to the vampires' wrath. As man and immortal clash, a reality-shattering threat looms. Hope resides solely in a new breed of hunter operating under the Vatican's authority. The true battle between holiness and evil has begun.

A near future, where humans have been defeated by the viral parasites named Gastrea. They have been exiled into a small territory and live in despair, side-by-side in terror.In this world trapped in darkness—Rentaro, a boy living near Tokyo and member of the "Civil Security"—an organization specializing in fighting against the Gastrea—is used to accomplishing dangerous tasks. His partner is Enju, a precocious young girl. They fight thanks to their peculiar powers until one day, when they receive a special assignment from the government. This top secret mission is to prevent the destruction of Tokyo...Set in a near future, this thrilling heroic-action story... starts now!

Thirty years after a disease that turns the infected into carnivorous insects emerged, a young exterminator and a teenage girl search for her mother.

Humans that have been physically altered and turned into dangerous weapons are known as the Extended. Juuzou Inui awakens as one of these weapons — with amnesia. But his job as an agent investigating the Extended leads to a mysterious child with Extended ties showing up at his office. Now Inui must keep the child away from street gangs and the megacorporation Berühren, and it won't be easy.

Shido's a midnight detective, half human and half vampire with no real memory of his past, who specializes in solving supernatural murders.Joined by Yayoi Matsunaga, a female government agent, Riho Yamazaki, an orphaned teenage girl working as his secretary and Guni, a little green imp, Shido must face demonic creatures known as Nightbreed.

The Diclonius, a mutated homo sapien that is said to be selected by God and will eventually become the destruction of mankind, possesses two horns in their heads, and has a "sixth sense" which gives it telekinetic abilities. Due to this dangerous power, they have been captured and isolated in laboratories by the government. Lucy, a young and psychotic Diclonius, manages to break free of her confines and brutally murder most of the guards in the laboratory, only to get shot in the head as she makes her escape. She survives and manages to drift along to a beach, where two teenagers named Kouta and Yuka discovers her. Having lost her memories, she was named after the only thing that she can now say, "Nyuu," and the two allow her to stay at Kouta's home. However, it appears that the evil "Lucy" is not dead just yet...

Years after the horrors of Raccoon City, Leon and Claire find themselves consumed by a dark conspiracy when a viral attack ravages the White House.

Ergo Proxy is a science fiction suspense anime television series, produced by Manglobe, which premiered across Japan on 25 February 2006 on the WOWOW satellite network. It is directed by Shukō Murase, with screenplay by Dai Satō et al.. Ergo Proxy has been described as a dark sciencefiction mystery with philosophical underpinnings. It features a combination of 2D digital cel animation, 3D computer modeling, and digital special effects.

In the 2030s Earth has been overrun by the Blue, which are mutated insect-like creatures that kill and harvest humans for food. Most of the surviving human race has moved to Second Earth, a huge spaceship that orbits the planet. Yuji and Marlene must work together to reach Second Earth and fight against the Blue.

Lain is an avant-garde anime influenced by philosophical subjects such as reality, identity, and communication. The series focuses on Lain Iwakura, an adolescent girl living in suburban Japan, and her introduction to the Wired, a global communications network similar to the Internet.

MegaTokyo, 2027. Relentless technological development has resulted in the creation of Boomers, artificially intelligent androids with the potential to free mankind from physical labor; but anything that can be used can also be misused.

If you are chosen by the bizarre black sphere known as the Gantz, you are already dead—yet you might be able to reclaim your mortality. First, the Gantz demands that you undertake brutal missions of madness, killing aliens hidden among the population. It is your only chance and you have no choice. You must play this disturbing game. And if you die again—and you likely will—it’s permanent.

Shy Natsu awakens as part of a group chosen to ensure the survival of humanity. Together, they have to survive on a changed Earth.

Japan in the near future suffers an unexplained major disaster. Five years later, reconstruction is well underway. Two young researchers at a university are pinning all their hopes on robot development. Now their new interpretation of the eternal hero Astro Boy up until his birth is just about to start!

Karen Kohiruimaki always felt out of place in the real world. Due to her extreme height, she found it hard to make friends with other girls her age. Everything changes when she's introduced to VR and Gun Gale Online. In GGO, Karen is free to play the cute, chibi avatar of her dreams! Can Karen find friendship in this bullet-ridden MMO...?

When the world is struck by a deadly pandemic that turns humans into zombies, Takashi Komuro and several of his classmates at Fujimi High School try to survive the apocalypse.

2150 A.D. The battle with the Festum, the silicon life-forms from distant outer space, had reached a new dimension. The North Polar Meir that was crushed during the First Azure Operation had dispersed its fragments all over the world. They all started activity on their own as independent Meirs. Most of the Meirs harbored hatred towards humanity and challenged a fight, however, a portion of the Festum chose coexistence with mankind. Amongst the crossfire, the Ryugujima island alone disappeared from the forefront of battle and continued its silence. The island had gained a means to converse with the Meir since their encounter with Misao Kurusu two years ago. The children of ALVISS had been searching for a way to understand the enemy as they prepared for battle. And now, once again, further evolution was about to befall the island. A girl that understands the language of the Festum, and a girl protected by a Festum. When the two meet, the doors to a new universe opens.

In Japan in the year 2035, an accident known as the "Burst" occurs during a research project, spawning an out-of-control artificial life form called "Matter" that has spread throughout the Kurobe Gorge. The research city that was once hailed as the hope for humanity is cordoned off by the government. Two years later, 15-year-old Aiko Tachibana, who lost her family in the Burst, learns something unbelievable from Yuya Kanzaki, a new student at her school. A secret is hidden within her body, and the answer to the puzzle lies at the "Primary Point" that was the center of the Burst. Aiko resolves to infiltrate the restricted area, escorted by a team of divers and with Yuya as her guide. When boy meets girl with the fate of humanity in their hands, what new truth will come to light?

The year is Post Disaster 323. More than 300 years after a great war between Earth and Mars known as the "Calamity War", Mars has been successfully terraformed and colonized by humans. However even with the technological advancements, the humans on Mars crave freedom against the government of Earth and seek to improve their livelihoods. Furthermore, while most of Mars' nations have received autonomy, the planet is virtually dependent on Earth for economic development. A young orphan named Mikazuki Augus is part of a group of children who work for the civilian security company Chryse Guard Security, entrusted with the safety of the Martian Princess Kudelia Aina Bernstein, who has plans for her nation of Chryse to secure independence from Earth. One day, the group was attacked by the Earth Military organization Gjallarhorn, which aims to stop the Martian independence movement. During the attack, the leader of the children and the Third Army Division within CGS, Orga Itsuka, decides to rebel against the adults and higher-ups who had escaped and left the children and foot-soldiers to remain and fight as decoys. Augus must now choose to either follow his friends, or his mission as he stumbles into the legendary mobile suit: the Gundam Barbatos.