20 best movies like Life as a Fatal Sexually Transmitted Disease (2000)

Inspired by a true story, a comedy centered on a 27-year-old guy who learns of his cancer diagnosis, and his subsequent struggle to beat the disease.

A powerful and emotional coming of age story, this remarkable tale is told with honesty and originality that will leave audiences moved. In the film, two outsiders, both shaped by the circumstances that have brought them together, forge a deep and lasting love. Directed by Gus Van Sant, one of the most astute observers of people living life on the edge, comes a take on friendship and young love as engaging and true as it is provocative and stirring.

A controlling father’s attempts to ensure that his two children succeed in high school backfire after his son experiences a career-ending sports injury. Their familial bonds are eventually placed under severe strain by an unexpected tragedy.

Benjamin Morton's life changed forever the day he met the little girl next door. Ava was and always would be the girl of his dreams. From the innocence of a childhood friendship, through adolescent attraction, their love strengthens and grows. When life takes a turn neither of them expected, their entire future is called into question.

An English chef with a chic restaurant on Bondi Beach trying to put his life and his relationship with his son back on track while surrounded by women.

Despite the tumor-shrinking medical miracle that has bought her a few years, Hazel has never been anything but terminal, her final chapter inscribed upon diagnosis. But when a patient named Augustus Waters suddenly appears at Cancer Kid Support Group, Hazel's story is about to be completely rewritten.

Cultural critic David Kepesh finds his life -- which he indicates is a state of "emancipated manhood" -- thrown into tragic disarray by Consuela Castillo, a well-mannered student who awakens a sense of sexual possessiveness in her teacher.

A young man is rocked by two announcements from his elderly father: that he has terminal cancer, and that he has a young male lover.

The friendship between two life-long girlfriends is put to the test when one starts a family and the other falls ill.

Arthur is a grumpy pensioner who can't understand why his wife Marion would want to embarrass herself singing silly songs with her unconventional local choir. But choir director Elizabeth sees something special in the reluctant Arthur and refuses to give up on him. As she coaxes him out of his shell, Arthur realizes that it is never too late to change.

Nelson is a man devoted to his advertising career in San Francisco. One day, while taking a driving test at the DMV, he meets Sara. She is very different from the other women in his life. Nelson causes her to miss out on taking the test and later that day she tracks him down. One thing leads to another and Nelson ends up living with her through a November that will change his life forever.

When Ross is diagnosed with terminal brain cancer and given six weeks to live, his newly engaged older brother Seth offers to spend his $50,000 wedding fund on a final trip of a lifetime. Their plans are complicated when Ross invites a call girl to join the group and Seth’s uptight fiancée insists on tagging along. This raucous road trip comedy features hip-hop star Asher Roth.

A girl dying of leukemia compiles a list of things she'd like to do before passing away. Topping the list is her desire to lose her virginity.

When college friends reunite after 15 years over the Christmas holidays, they discover just how easy it is for long-forgotten rivalries and romances to be reignited.

I Origins follows a molecular biologist studying the evolution of the human eye. He finds his work permeating his life after a brief encounter with an exotic young woman who slips away from him. As his research continues years later with his lab partner, they make a stunning scientific discovery that has far reaching implications and complicates both his scientific and and spiritual beliefs. Traveling half way around the world, he risks everything he has ever known to validate his theory.

When new kid in town Ed Wallis is given an assignment to interview an older person, he turns to his mysterious neighbor, Ashby Holt for help. That new connection leads to unexpected journeys for both of them, as Ashby – who turns out to be a retired CIA assassin – deals with a terminal prognosis, and Ed deals with adjusting to life with his newly single mom and developing relationship with a brainy classmate, Eloise.

Liverpool, 1978: What starts as a vibrant affair between a legendary femme-fatale, the eccentric Academy Award-winning actress Gloria Grahame, and her young lover, British actor Peter Turner, quickly grows into a deeper relationship, with Turner being the person Gloria turns to for comfort.

Lee, a former Western film icon, is living a comfortable existence lending his golden voice to advertisements and smoking weed. After receiving a lifetime achievement award and unexpected news, Lee reexamines his past, while a chance meeting with a sardonic comic has him looking to the future.

Retreating from life after a tragedy, a man questions the universe by writing to Love, Time and Death. Receiving unexpected answers, he begins to see how these things interlock and how even loss can reveal moments of meaning and beauty.

After learning that his terminally ill wife has six months to live, a man welcomes the support of his best friend who moves into their home to help out.

A musical romantic movie exploring the journey that ensues when the blue blooded boy Inder, "Who wanted to love no one" crosses paths with Saru, "Whom no one wanted to love". All their lives they were waiting to meet, but they just didn't know it . A musical tale of love , longing and loss. Sanam Teri Kasam - A Love story sealed with a Curse.

A couple's wedding plans are thrown off course when the groom is diagnosed with liver cancer.

Juha has lost his wife in an accident. Years after, he still feels numb and unable to connect with people. Meeting Mona, a dominatrix, changes everything.

Two young guys in a bar hit on the woman they fancy by sending one of them over who tells her that the other one is terminally ill...

About three generations of a family grappling with a life-changing experience during one day of a vacation in the historic town of Sintra, Portugal.

Set in the late '20s. A thirtyish young man, who heads a small factory, faints at the funeral of a close friend. He decides to go home to his aunt and uncle for a while, but gets involved with a family of five women who had been in love with him at one time though he had apparently loved only one, who, unknown to him, has died since his departure. The women are mainly disillusioned with life or estranged from husbands while the youngest has a crush on him.

A young widow discovers that her late husband has left her 10 messages intended to help ease her pain and start a new life.

A woman embarks on a journey alone across the United States after fleeing from her violent husband.

A beautiful story about youth, love, friendship and the pursuit of adventure during the bloody and brutal reality of the Warsaw Uprising.

Aged, embittered widower, Fred learns to enjoy life thanks to his elderly yet vibrant neighbor, Elsa. Upon learning Elsa is terminally ill, Fred takes her to the Fontana di Trevi in Rome in order to reenact her favorite scene from ‘La Dolce Vita’.

Spanning over one thousand years, and three parallel stories, The Fountain is a story of love, death, spirituality, and the fragility of our existence in this world.

Roméo and Juliette are two young actors. They fall in love at first sight, move in together and make a baby. A love story and the founding of a home like millions of others. Except that their little boy, Adam, behaves abnormally. The young parents try hard to persuade themselves that everything is okay but, with the passing of time, they cannot delude themselves anymore: their son has a problem. From now on, war is declared. A war against illness. A war against Death. A war against despair.

Set in 1945, in Pre-Independent India, the elite, opulent and solemn world of the Chaudhry family, and the wild, mysterious and musical underbelly of the town, Hira Mandi, clash when Roop Chaudhry encounters Zafar, a daredevil from Hira Mandi, unleashing deep-buried truths, secrets of betrayal and affairs that threaten to bring both worlds crashing down.

Travis and Gabby first meet as neighbors in a small coastal town and wind up in a relationship that is tested by life's most defining events.

Turin, 1969. Nine-year-old Massimo’s idyllic childhood is shattered by the mysterious death of his mother. The young boy refuses to accept this brutal loss, even if the priest says she is now in Heaven. Years later in the 90s, adult Massimo has become an accomplished journalist. After reporting on the war in Sarajevo, he begins to suffer from panic attacks. As he prepares to sell his parents’ apartment, Massimo is forced to relive his traumatic past. Compassionate doctor Elisa could help tormented Massimo open up and confront his childhood wounds…

When an itinerant reluctantly returns home to help his sickly mother run her shop, they're both tempted to turn to crime to help make ends meet.

New Jersey car mechanic Stacie Andree and her police detective girlfriend Laurel Hester both battle to secure Hester's pension benefits after she was diagnosed with a terminal illness.

Handsome Dutchman Stijn is the star of an advertising agency with his buddy Frenk and a hot womanizer. The boys start their own agency and Stijn marries colleague Carmen, who accepts his incurable greed for truly meaningless one-night-stands. Even fatherhood and a move to the boring country go well, until Carmen gets breast cancer. Now their lives are turned upside-down, maybe wrecked

The story of a husband who suspects his wife of adultery, and sets out to track down the other man in her life.

Despite grumpy 59 year-old Ove being deposed as president of his condominium association, but he keeps looking over the neighbourhood with an iron fist. When pregnant Parvaneh and her family move into the terraced house opposite Ove and she accidentally back into Ove’s mailbox, it sets off a series of unexpected changes in his life.

A world-weary college professor is given a life-changing diagnosis and decides to throw all pretense and conventions to the wind and live his life as boldly and freely as possible with a biting sense of humor, a reckless streak and a touch of madness.

A couple who have known each other since 8 are destined to be together until death do them apart.

Hanna and Simon are in a 20 year marriage with an unexiting relationship. By chance, they both meet and start separate affairs with Adam. Adam has no idea that his two lovers are married, until they are all found out when Hanna becomes pregnant, with the natural doubts stemming from their situation.

Nick, a gay, HIV-positive architect, begins to display severe symptoms of AIDS and makes preparations to kill himself before he is unable to function normally. He arranges a party to reconnect and say goodbye to his closest friends and his confused parents. But when his ex-partner, Brandon, a television director who left Nick when he was diagnosed with HIV, shows up, what was supposed to be a celebratory event becomes much more difficult for everyone.

Seventeen-year-old Stella spends most of her time in the hospital as a cystic fibrosis patient. Her life is full of routines, boundaries and self-control -- all of which get put to the test when she meets Will, an impossibly charming teen who has the same illness.

A Pedro Almodovar production in which a fatally ill mother with only two months to live creates a list of things she wants to do before she dies with out telling her family of her illness.

A group of friends at a Jerusalem retirement home build a machine for self-euthanasia in order to help their terminally ill friend. When rumors of the machine begin to spread, more and more people ask for their help, and the friends are faced with an emotional dilemma

Alexander, a famous writer, is very ill and has only a few days to live. He meets a little boy on the street, who is an illegal immigrant from Albania. Alexander then takes the boy home.

Based on a true story. 16-year old Steffi just graduated from high school and is very much looking forward to her class trip to Paris where she has promised her boyfriend Fabian the romantic night that she has kept him waiting for since they started dating. Her lifelong plan to join the police forces is already set up which means her adult life is right around the corner. At a routine health check-up, just before the trip to Paris, Steffi and her parents are faced with a shattering diagnosis: Incurable cancer with a life expectancy of less than a year. While her mother Eva immediately tries to helplessly protect Steffi from everything, let alone a school trip to Paris and her father Frank, a protestant priest, questions everything he ever believed in, but Steffi is determined to shake off her doomed destiny.

When 19-year-old gay-rights activist Tommy and 24-year-old Alan first meet in 1973, they find themselves on the opposite sides of the political coin...