20 Best Anime series like Appleseed (2004)

The story revolves around Duke Fleed who is a survivor of the Vega Star, raised by Dr. Umon as his adoptive son, and known as Daisuke Umon on Earth. Years after his arrival, he's faced with the threat of King Vega and his army, who want to conquer the Earth. With his friends Koji and Hikaru (and later his kid sister Maria Grace), Duke decides to fight back using his best weapon, the almighty Grendizer.

In the year 2063, eight high school students and a kid are flown out to Planet Camp, tasked with surviving on their own for a few days. But shortly after arriving, an ominous glowing orb warps them to an unknown quadrant of space, nearly 5,012 light years away. Now, the only way back home is a slow, dangerous trek across the universe—a journey that’ll test them in ways Planet Camp never could.

Ergo Proxy is a science fiction suspense anime television series, produced by Manglobe, which premiered across Japan on 25 February 2006 on the WOWOW satellite network. It is directed by Shukō Murase, with screenplay by Dai Satō et al.. Ergo Proxy has been described as a dark sciencefiction mystery with philosophical underpinnings. It features a combination of 2D digital cel animation, 3D computer modeling, and digital special effects.

Tokyo is abuzz with persocoms – humanoid computers that are virtually perfect. The socially and technologically inept Hideki is dying to get his hands on one. When he finds Chii abandoned in the trash, she’s cuter than any current model he’s ever seen before. But when he gets her home and turns her on, she has no data and only a single learning program installed. While Hideki puts his whole heart into teaching Chii the ins and outs of humanity, a mystery unfolds as a dark secret within her awakens.

Forty years ago, the minds of Paradigm City's inhabitants were wiped clean of all recollections of the past. Now, ruled by a powerful corporation and cut off from the rest of the world by desolate wastelands, Paradigm has become a virtual police state where Negotiators like Roger Smith keep the wheels of progress, commerce, and society turning.

The year is Post Disaster 323. More than 300 years after a great war between Earth and Mars known as the "Calamity War", Mars has been successfully terraformed and colonized by humans. However even with the technological advancements, the humans on Mars crave freedom against the government of Earth and seek to improve their livelihoods. Furthermore, while most of Mars' nations have received autonomy, the planet is virtually dependent on Earth for economic development. A young orphan named Mikazuki Augus is part of a group of children who work for the civilian security company Chryse Guard Security, entrusted with the safety of the Martian Princess Kudelia Aina Bernstein, who has plans for her nation of Chryse to secure independence from Earth. One day, the group was attacked by the Earth Military organization Gjallarhorn, which aims to stop the Martian independence movement. During the attack, the leader of the children and the Third Army Division within CGS, Orga Itsuka, decides to rebel against the adults and higher-ups who had escaped and left the children and foot-soldiers to remain and fight as decoys. Augus must now choose to either follow his friends, or his mission as he stumbles into the legendary mobile suit: the Gundam Barbatos.

Following the success in the Camelot Singularity, Ritsuka Fujimaru and Mash Kyrielight are assigned to the last Singularity in the Grand Order initiative. In Ancient Babylonia, 2500 BCE, they embark on a mission to secure humanity's survival. Upon arrival, they learn that three gods have threatened Uruk, the Babylonian city ruled by King Gilgamesh. Ritsuka and Mash must work together to fend off the invasion of mysterious beasts in Uruk under Gilgamesh's orders while investigating the true nature of the three gods' actions against humanity; but unknown to Ritsuka, an ancient entity is slowly rising from its slumber.

In the 2030s Earth has been overrun by the Blue, which are mutated insect-like creatures that kill and harvest humans for food. Most of the surviving human race has moved to Second Earth, a huge spaceship that orbits the planet. Yuji and Marlene must work together to reach Second Earth and fight against the Blue.

One fateful day, all of humanity was petrified by a blinding flash of light. After several millennia, high schooler Taiju awakens and finds himself lost in a world of statues. However, he's not alone! His science-loving friend Senku's been up and running for a few months and he's got a grand plan in mind, to kickstart civilization with the power of science!

Invertia was a meteor storm that caused an unprecedented disaster during the 20th century. Because of this disaster, numerous cities around the world were destroyed. However, within the meteor, an unknown element called mana was discovered. It allowed human technology to make rapid strides giving rise to a new species of super-powered humans, the Star Pulse Generation (Genestella). The Festas (Star Warrior Festivals) host battles between Genestella at a city of six academies called “Rikka,” also commonly known as “Asterisk.”Scholarship student Ayato Amagiri transferred into Seidoukan Academy in order to fulfill his own wish, swearing he too will fight in this city.

In the year 2045, after global capitalism has defaulted, Japan's elite Section 9 begins conducting covert cyber operations.

During the construction of the Kurobe Dam, an ancient artifact was discovered, and so the United Nations Kurobe Research Institute was established. Intellectuals from all over the world gathered to study the object, and the children of those researchers attend Mt. Tate International Senior High School, including the institute head's daughter, Yukina Shirahane. In the summer of 2016, a lone samurai once again awakens.

15 years ago, an unknown hyperspace gate opened over the Pacific. Beyond this gate lies Reto Semaani, a strange alternate world where fairies and monsters live.San Teresa City—a city where over two million immigrants live from both worlds. As a result, there are the haves and the have-nots. Here is the world's newest "city of dreams." But in the shadow of the chaos, crime is rampant: drugs, prostitution, and weapon trafficking. The detectives who stand up to these heinous crimes are in the San Teresa City Police. When the detective Kei Matoba and the alternate-world knight Tirana—two individuals who differ in gender, personality, and even world of origin—meet, an incident erupts. Two worlds. Two justices. From this, the curtain rises on a buddy police action story!

In Japan in the year 2035, an accident known as the "Burst" occurs during a research project, spawning an out-of-control artificial life form called "Matter" that has spread throughout the Kurobe Gorge. The research city that was once hailed as the hope for humanity is cordoned off by the government. Two years later, 15-year-old Aiko Tachibana, who lost her family in the Burst, learns something unbelievable from Yuya Kanzaki, a new student at her school. A secret is hidden within her body, and the answer to the puzzle lies at the "Primary Point" that was the center of the Burst. Aiko resolves to infiltrate the restricted area, escorted by a team of divers and with Yuya as her guide. When boy meets girl with the fate of humanity in their hands, what new truth will come to light?

The story is set in the distant future. The land is ruined, and humanity establishes the mobile fort city Plantation. Pilots produced inside Plantation live in Mistilteinn, also know as the "birdcage." Children live there knowing nothing of the outside world or the freedom of the sky. Their lives consist of battling to carry out missions. Their enemies are mysterious giant lifeforms known as Kyouryuu, and the children pilot robots called Franxx to face off against them. For the children, riding the Franxx proves their existence. A boy named Hiro is called Code:016, and he was once known as a prodigy. However, he has fallen behind, and his existence seems unnecessary. Not piloting a Franxx is the same as ceasing to exist. One day, a mysterious girl known as "Zero Two" appears before him. Two horns grow out of her head.

Inuyashiki Ichirou is down on his luck. While only 58 years old, his geriatric looks often have him written off as a pathetic old man by the world around him and he’s constantly ignored and disrespected by his family despite all that he’s done to support them. On top of everything else, his doctor has revealed that he has cancer and it appears that he has little time left in this world. But just when it seems things couldn’t get any worse, a blinding light in the night sky strikes the earth where Ichirou stands. He later wakes up to find himself unscathed, but he soon starts to notice that there’s something… different about himself. However, it turns out that these strange, new changes are just what Ichirou needs to take a new lease on life and now it seems like there’s nothing to stop him from being a hero worthy of the respect that he never had before… unless, that is, there was someone else out there with these same changes…

In the early 2050s, unknown life forms called “Oracle cells” begin their uncontrolled consumption of all life on Earth. Their ravenous appetite and remarkable adaptability earn them first dread, then awe, and finally the name “aragami”. In the face of an enemy completely immune to conventional weapons, urban civilization collapses, and each day humanity is driven further and further toward extinction. One single ray of hope remains for humanity. Following the development of “God Arcs”—living weapons which incorporate Oracle cells—their wielders are organized into an elite force.

The story centers around two fiercely fighting schoolgirls, Ryuuko Matoi and Satsuki Kiryuuin. On a campus ruled by force, a transfer student wielding a Basami sword brings about upheaval.

In 2019, Kaito Yashio and Akiho Senomiya are the sole members of the Robotics Club at Central Tanegashima High School in Kyushu, Japan. Kaito is a laid back student and a skilled gamer who is just trying to help Akiho, his childhood friend. She is an energetic positive-thinking girl who yearns to complete the ongoing project of the club: building a functional replica of Gunvarrel, the main robot of a once popular TV series. As they gather new members and try to assemble the robot, Kaito starts stumbling upon secret reports that might reveal a conspiracy of large proportions. Unaware of what he is actually dealing with, Kaito little by little starts discovering clues laid by the mysterious Ko Kimijima.

With a maintenance robot and a deadly fugitive tagging along, friendship droid S.A.M searches for its best friend, the heir to a kingdom under siege.

A near future, where humans have been defeated by the viral parasites named Gastrea. They have been exiled into a small territory and live in despair, side-by-side in terror.In this world trapped in darkness—Rentaro, a boy living near Tokyo and member of the "Civil Security"—an organization specializing in fighting against the Gastrea—is used to accomplishing dangerous tasks. His partner is Enju, a precocious young girl. They fight thanks to their peculiar powers until one day, when they receive a special assignment from the government. This top secret mission is to prevent the destruction of Tokyo...Set in a near future, this thrilling heroic-action story... starts now!

Many years ago, a Great Civil War ravaged Japan, leaving the country fragmented between two regions: Kansai and Kanto. In Kansai, a group of six Akudama carry out missions given to them by a mysterious black cat, while evading the police. But a dangerous journey is about to unfold when a civilian girl becomes twisted into the Akudama's way of life and witnesses their criminal drives.

Angel Beats takes place in the afterlife and focuses on Otonashi, a boy who lost his memories of his life after dying. He is enrolled into the afterlife school and meets a girl named Yuri who invites him to join the Afterlife Battlefront — an organization she leads which fights against God. The Battlefront fight against the student council president Angel, a girl with supernatural powers.

Many years have passed since humanity was driven to the brink of extinction by the sudden emergence of the unknown life forms Gadoll. Those humans that survived now dwell in a 3000m-high mobile fortress Deca-dence built to protect themselves from the Gadoll threat.Denizens of Deca-dence fall into two categories: Gears, warriors who fight the Gadoll daily, and Tankers, those without the skills to fight. One day, Natsume, a Tanker girl who dreams of becoming a Gear meets surly Kaburagi, an armor repairman of Deca-dence.This chance meeting between the seemingly two opposites, the girl with a positive attitude who never gives up on her dreams and the realist who has given up on his, will eventually shake the future course of this world.

A samurai lord has bartered away his newborn son's organs to forty-eight demons in exchange for dominance on the battlefield. Yet, the abandoned infant survives thanks to a medicine man who equips him with primitive prosthetics—lethal ones with which the wronged son will use to hunt down the multitude of demons to reclaim his body one piece at a time, before confronting his father. On his journeys the young hero encounters an orphan who claims to be the greatest thief in Japan.

For Brandon Heat, death doesn't matter. Driven by his need for revenge, he returns from beyond the grave to cripple Milleneon, the huge mafia organization which uses undead monsters as its enforcers. His ultimate goal is to destroy Harry MacDowel, the leader of Milleneon and, at one time, Brandon's best friend...

Alcohol, smoking, and stress—in the body subjected to these irritants, the cells responsible for maintaining life seem to fight a war that never ends. Due to a severe shortage of workers, Red Blood Cell AA2153 has to quickly learn to deliver oxygen and collect carbon dioxide, even in dangerous conditions. Meanwhile, White Blood Cell U-1196 has to do her part by dealing with germs and viruses during life-threatening situations. In the midst of these crises, they have to work together to keep the body healthy, despite not knowing if their sacrifices will be worthwhile. Cells at Work! Code Black takes a different approach by showing the grittier side of the jobs our cells perform.

Btooom!, stylized as BTOOOM!, is a Japanese manga series written by Jun'ya Inoue and serialized in Weekly Comic Bunch and later in Monthly Comic Bunch. An anime adaptation by Madhouse aired in Japan on Tokyo MX and was streamed with English subtitles by Crunchyroll from October 4 to December 20, 2012. It has been licensed in North America by Sentai Filmworks.

The one adored as the mother is not the real parent. The people living here together are not actual siblings. The Gracefield House is where orphaned children live. An irreplaceable home where 38 siblings and Mom live happy lives, even with no blood relations. However, their everyday life suddenly came to an abrupt end one day...

Seventeen-year-old Hajime Nagumo is your average, everyday otaku. However, his simple life of pulling all-nighters and sleeping in school is suddenly turned upside down when he, along with the rest of his class, is summoned to a fantasy world! They're treated like heroes and tasked with the duty of saving the human race from utter extinction. But what should have been any otaku's wet dream quickly turns into Hajime's nightmare. While the rest of his class are blessed with godlike powers, Hajime's job, Synergist, only has a single transmutation skill. Ridiculed and bullied by his classmates for being weak, he soon finds himself in despair. Will he be able to survive in this dangerous world of monsters and demons with only a glorified blacksmith's level of strength?

Rinka Urushiba is a normal high school girl, until she encounters a penguin and shoals of glowing fish swimming through the sky. She looses consciousness only to awaken with the power to move through inanimate objects. At first she thought it was a hallucination if it were not for Kyotaro Azuma who witnessed the event and who, incidentally, has the ability to teleport. They decide to use their powers to combat people who might use their powers for evil.

Humans have created many stories. Joy, sadness, anger, deep emotion. Stories shake our emotions, and fascinate us. However, these are only the thoughts of bystanders. But what if the characters in the story have "intentions"? To them, are we god-like existences for bringing their story into the world? Our world is changed. Mete out punishment upon the realm of the gods. In Re:CREATORS, everyone becomes a Creator.

Girls from all over the world gather at IS Academy to learn how to become IS pilots. However, since Ichika can somehow pilot the IS even though he is male, he was forced to attend IS Academy as the only male in this school.

One night, Kyouhei and Hibino discover a dead body and coincidentally Kyouhei’s sister appears with the doll called Kamisama she controls.

A gate to another dimension has burst open, and from it emerge gigantic invincible creatures that threaten all of humanity. Earth's only defense is a mysterious group of warriors who have co-opted the alien technology in order to fight back!

In 1972, the Apollo 17 mission discovered a hypergate to Mars on the surface of the moon. Soon a war breaks out between Earth and Mars, and Martian soldiers begin to descend from the sky, riding steel giants, intent on exterminating humanity.

An isolated city. An unknown enemy. An uncertain past and a prophecy of the future. The children fight the "future" to bring back the "present". No matter what, they're going home...

After rescuing Last Order and subsequently taking a bullet to the head, Academy City’s top-ranked esper rests in the hospital. But Accelerator’s recovery is cut short when a mysterious girl carrying a photo of his little clone companion asks for help. Now they’re taking on Disciplinary Action—an anti-evil coalition whose sinister plans threaten Last Order, Academy City, and even the entire world!

2150 A.D. The battle with the Festum, the silicon life-forms from distant outer space, had reached a new dimension. The North Polar Meir that was crushed during the First Azure Operation had dispersed its fragments all over the world. They all started activity on their own as independent Meirs. Most of the Meirs harbored hatred towards humanity and challenged a fight, however, a portion of the Festum chose coexistence with mankind. Amongst the crossfire, the Ryugujima island alone disappeared from the forefront of battle and continued its silence. The island had gained a means to converse with the Meir since their encounter with Misao Kurusu two years ago. The children of ALVISS had been searching for a way to understand the enemy as they prepared for battle. And now, once again, further evolution was about to befall the island. A girl that understands the language of the Festum, and a girl protected by a Festum. When the two meet, the doors to a new universe opens.

Eager to follow in the footsteps of his fallen sister, Kazuya enrolls at West Genetics Academy, a training facility for buxom heroes known as Pandoras. These courageous schoolgirls are genetically-enhanced with enough sex appeal to cripple a man – and the superhuman strength to slaughter aliens by the dozen. Kazuya’s role is that of Limiter, a Pandora’s battle partner, and he quickly sets his sights on the most feared beauty in school, Satellizer el Bridget. This full-figured annihilator of aliens is as desirable as she is deadly, but rubbing her the wrong way could lead to gross bodily harm. Can Kazuya forge a bond with his new partner and rise to the top of the ranks at West Genetics? Or will he fall victim to the mysterious bloodlust lurking within Satellizer?

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The Universal Century, a history marked by space colonization and space warfare, has passed. Humanity's prosperity, which ushered in a new era known as Regild Century (R.C.), was believed to endure alongside the global peace. Beruri Zenamu a pilot in training of the of the Capitol Guard is somehow chosen by the G-Serufu - a highly maneuverable Mobile Suit of unknown origin - to lead to uncover hidden truths that will shake the peace of the Regild Century era.