20 Best Anime series like Program (2003)

In the early 2050s, unknown life forms called “Oracle cells” begin their uncontrolled consumption of all life on Earth. Their ravenous appetite and remarkable adaptability earn them first dread, then awe, and finally the name “aragami”. In the face of an enemy completely immune to conventional weapons, urban civilization collapses, and each day humanity is driven further and further toward extinction. One single ray of hope remains for humanity. Following the development of “God Arcs”—living weapons which incorporate Oracle cells—their wielders are organized into an elite force.

Wolverine is a mutant, possessing animal-keen senses, enhanced physical capabilities, three retracting bone claws on each hand and a healing factor that allows him to recover from virtually any wound, disease or toxin at a accelerated rate.

With a maintenance robot and a deadly fugitive tagging along, friendship droid S.A.M searches for its best friend, the heir to a kingdom under siege.

Legendary half-vampire, half-human vampire hunter Blade is tracking Deacon Frost, a very powerful and influential vampire who killed his mother and who heads Existence, a secretive vampire organization that operates in Southeast Asia.

The anime's story is set in the year 2202, three years after the Yamato's return from the planet Iscandar. The people of Earth restored their planet with the Cosmo Reverse System, and they signed a peace treaty with Garmillas. In addition to reconstruction, Earth developed a new defense fleet that includes the state-of-the-art battleship Andromeda. The Earth goes down a path of military expansion, despite Starsha Iscandar's wishes. The Yamato helps accomplish this so-called peace, but it comes at the price of many invaluable sacrifices. The goddess Teresa, who prays for tranquility in space, calls the Yamato to a new voyage. The threat of Gatlantis is sweeping over the universe and approaching Earth.

15 years ago, an unknown hyperspace gate opened over the Pacific. Beyond this gate lies Reto Semaani, a strange alternate world where fairies and monsters live.San Teresa City—a city where over two million immigrants live from both worlds. As a result, there are the haves and the have-nots. Here is the world's newest "city of dreams." But in the shadow of the chaos, crime is rampant: drugs, prostitution, and weapon trafficking. The detectives who stand up to these heinous crimes are in the San Teresa City Police. When the detective Kei Matoba and the alternate-world knight Tirana—two individuals who differ in gender, personality, and even world of origin—meet, an incident erupts. Two worlds. Two justices. From this, the curtain rises on a buddy police action story!

Alcohol, smoking, and stress—in the body subjected to these irritants, the cells responsible for maintaining life seem to fight a war that never ends. Due to a severe shortage of workers, Red Blood Cell AA2153 has to quickly learn to deliver oxygen and collect carbon dioxide, even in dangerous conditions. Meanwhile, White Blood Cell U-1196 has to do her part by dealing with germs and viruses during life-threatening situations. In the midst of these crises, they have to work together to keep the body healthy, despite not knowing if their sacrifices will be worthwhile. Cells at Work! Code Black takes a different approach by showing the grittier side of the jobs our cells perform.

One day, New York City as we know it vanished overnight into a mysterious fog. Now known as Hellsalem's Lot, it has become a place where another world beyond imagining is connected to our reality. The balance within this new world is protected by a secret society known as Libra. Leo, a journalist and photographer who arrives in the city, is unexpectedly recruited to join their ranks.

Ren Amamiya is about to enter his second year after transferring to Shujin Academy in Tokyo. Following a particular incident, his Persona awakens, and together with his friends, they form the “Phantom Thieves of Hearts” to reform hearts of corrupt adults by stealing the source of their distorted desires. Meanwhile, bizarre and inexplicable crimes have been popping up one after another… Living an ordinary high school life in Tokyo during the day, the group maneuvers the metropolitan city as Phantom Thieves after hours. Let the curtain rise for this grand, picaresque story!

With the casualties of war still haunting him, young Levius uses his prosthetic arm to take his fight into the brutal world of Mecha Boxing.

Sōya Kuroi has dreams of people with superpowers fighting a massive dragon in the sky, but his real life is almost as weird. He's had amnesia for about two weeks and been taken in by a maid and an anthropomorphic cat. When a UFO in the shape of a stuffed bear approaches Sorimasaka City and other metros around the world, he's startled to see seven rainbow-sparkling heroes zoom out to confront it – just like in his dream. Even weirder, the maid wants him to leave his shelter to confront these heroes and take the source of their power.

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A gate to another dimension has burst open, and from it emerge gigantic invincible creatures that threaten all of humanity. Earth's only defense is a mysterious group of warriors who have co-opted the alien technology in order to fight back!

In 1972, the Apollo 17 mission discovered a hypergate to Mars on the surface of the moon. Soon a war breaks out between Earth and Mars, and Martian soldiers begin to descend from the sky, riding steel giants, intent on exterminating humanity.

An isolated city. An unknown enemy. An uncertain past and a prophecy of the future. The children fight the "future" to bring back the "present". No matter what, they're going home...

In Japan in the year 2035, an accident known as the "Burst" occurs during a research project, spawning an out-of-control artificial life form called "Matter" that has spread throughout the Kurobe Gorge. The research city that was once hailed as the hope for humanity is cordoned off by the government. Two years later, 15-year-old Aiko Tachibana, who lost her family in the Burst, learns something unbelievable from Yuya Kanzaki, a new student at her school. A secret is hidden within her body, and the answer to the puzzle lies at the "Primary Point" that was the center of the Burst. Aiko resolves to infiltrate the restricted area, escorted by a team of divers and with Yuya as her guide. When boy meets girl with the fate of humanity in their hands, what new truth will come to light?

Many years have passed since humanity was driven to the brink of extinction by the sudden emergence of the unknown life forms Gadoll. Those humans that survived now dwell in a 3000m-high mobile fortress Deca-dence built to protect themselves from the Gadoll threat.Denizens of Deca-dence fall into two categories: Gears, warriors who fight the Gadoll daily, and Tankers, those without the skills to fight. One day, Natsume, a Tanker girl who dreams of becoming a Gear meets surly Kaburagi, an armor repairman of Deca-dence.This chance meeting between the seemingly two opposites, the girl with a positive attitude who never gives up on her dreams and the realist who has given up on his, will eventually shake the future course of this world.

Inuyashiki Ichirou is down on his luck. While only 58 years old, his geriatric looks often have him written off as a pathetic old man by the world around him and he’s constantly ignored and disrespected by his family despite all that he’s done to support them. On top of everything else, his doctor has revealed that he has cancer and it appears that he has little time left in this world. But just when it seems things couldn’t get any worse, a blinding light in the night sky strikes the earth where Ichirou stands. He later wakes up to find himself unscathed, but he soon starts to notice that there’s something… different about himself. However, it turns out that these strange, new changes are just what Ichirou needs to take a new lease on life and now it seems like there’s nothing to stop him from being a hero worthy of the respect that he never had before… unless, that is, there was someone else out there with these same changes…

Angel Beats takes place in the afterlife and focuses on Otonashi, a boy who lost his memories of his life after dying. He is enrolled into the afterlife school and meets a girl named Yuri who invites him to join the Afterlife Battlefront — an organization she leads which fights against God. The Battlefront fight against the student council president Angel, a girl with supernatural powers.

The deep sea fleet has taken control of the world's oceans. The only counter against this adversary are the kanmusu (ship girls) which have the ability to equip weapons in the spirit of their former Japanese warship counterparts. This series revolves around destroyer class as she arrives at the naval base for the start of her training.

The Universal Century, a history marked by space colonization and space warfare, has passed. Humanity's prosperity, which ushered in a new era known as Regild Century (R.C.), was believed to endure alongside the global peace. Beruri Zenamu a pilot in training of the of the Capitol Guard is somehow chosen by the G-Serufu - a highly maneuverable Mobile Suit of unknown origin - to lead to uncover hidden truths that will shake the peace of the Regild Century era.

In the year 2045, after global capitalism has defaulted, Japan's elite Section 9 begins conducting covert cyber operations.

Brought together by a mysterious song, a grad student and an engineer lead the fight against an unimaginable force that may spell doom for the world.

Based on Sakyo Komatsu's 1973 bestseller sci-fi novel "Japan Sinks." The story is set right after the 2020 Tokyo Summer Olympics, and follows the fate of the four members of the Muto family, including the protagonist girl Ayumu and her younger brother Gou.

In the year 2063, eight high school students and a kid are flown out to Planet Camp, tasked with surviving on their own for a few days. But shortly after arriving, an ominous glowing orb warps them to an unknown quadrant of space, nearly 5,012 light years away. Now, the only way back home is a slow, dangerous trek across the universe—a journey that’ll test them in ways Planet Camp never could.

The year is Post Disaster 323. More than 300 years after a great war between Earth and Mars known as the "Calamity War", Mars has been successfully terraformed and colonized by humans. However even with the technological advancements, the humans on Mars crave freedom against the government of Earth and seek to improve their livelihoods. Furthermore, while most of Mars' nations have received autonomy, the planet is virtually dependent on Earth for economic development. A young orphan named Mikazuki Augus is part of a group of children who work for the civilian security company Chryse Guard Security, entrusted with the safety of the Martian Princess Kudelia Aina Bernstein, who has plans for her nation of Chryse to secure independence from Earth. One day, the group was attacked by the Earth Military organization Gjallarhorn, which aims to stop the Martian independence movement. During the attack, the leader of the children and the Third Army Division within CGS, Orga Itsuka, decides to rebel against the adults and higher-ups who had escaped and left the children and foot-soldiers to remain and fight as decoys. Augus must now choose to either follow his friends, or his mission as he stumbles into the legendary mobile suit: the Gundam Barbatos.