American series about epidemics and viruses

List of the best American TV shows about epidemics and viruses, selected by visitors to our site: Resident Evil: Infinite Darkness, The Rain, The Stand, Castlevania, Z Nation, The Last Kids on Earth, Death Valley, See, Pandemic: How to Prevent an Outbreak, 12 Monkeys.

In the top there are new series of 2023, a plot description and trailers for series that have already been released.

Country
Markimdb: 5.7
Genrehorror, fantastic, action, cartoon, anime
CountryJapan, USA

Years after the horrors of Raccoon City, Leon and Claire find themselves consumed by a dark conspiracy when a viral attack ravages the White House.

Markimdb: 6.3
Genrefantastic, thriller, drama
CountryDenmark, USA
Duration02:13

After a brutal virus wipes out most of the population, two young siblings embark on a perilous search for safety. A Scandinavian thriller series.

Markimdb: 5.5
Genrehorror, fantastic, thriller, fantasy, drama, adventure
CountryUSA

In a world mostly wiped out by the plague and embroiled in an elemental struggle between good and evil, the fate of mankind rests on the frail shoulders of the 108-year-old Mother Abagail and a handful of survivors. Their worst nightmares are embodied in a man with a lethal smile and unspeakable powers: Randall Flagg, the Dark Man.

Markimdb: 8.3
Genrehorror, action, fantasy, cartoon
CountryUSA
Duration01:46

A dark medieval fantasy following the last surviving member of the disgraced Belmont clan, trying to save Eastern Europe from extinction at the hand of Vlad Dracula Tepe himself. Inspired by the classic video game series.

Markimdb: 6.7
Genrehorror, fantastic, action, comedy, melodrama, drama
CountryUSA
Duration00:43

    Three years after the zombie virus has gutted the country, a team of everyday heroes must transport the only known survivor of the plague from New York to California, where the last functioning viral lab waits for his blood.

    Markimdb: 7.2
    Genrehorror, comedy, adventure, family, cartoon
    CountryUSA

    Young teenager Jack Sullivan and a group of friends live in a decked-out tree house, playing video games, eating candy, and fighting zombies in the aftermath of a monster apocalypse.

    Markimdb: 7.8
    Genrehorror, comedy
    CountryUSA
    Duration00:22

    A year ago, vampires, werewolves and zombies mysteriously descended upon the streets of California's San Fernando Valley. The Undead Task Force (UTF) was created to combat the emergence of monsters.

    Markimdb: 7.6
    Genrefantastic, action, drama
    CountryUSA

    A virus has decimated humankind. Those who survived emerged blind. Centuries later when twins are born with the mythic ability to see, their father must protect his tribe against a threatened queen.

    Markimdb: 6.4
    Genredocumentary
    CountryUSA

    In this docuseries, meet the heroes on the front lines of the battle against influenza and learn about their efforts to stop the next global outbreak.

    Markimdb: 7.7
    Genrefantastic, thriller, drama, adventure, detective
    CountryUSA
    Duration00:42

    The provocative story of Cole, a time traveler from a decimated future in a high-stakes race against the clock. Utilizing a dangerous and untested method of time travel, he journeys from 2043 to the present day on a mission to locate and eradicate the source of a deadly plague that will all but annihilate the human race.

    Markimdb: 8.4
    Genrehorror, action, fantasy, comedy
    CountryUSA
    Duration01:27

    Bruce Campbell reprises his role as Ash Williams, an aging lothario and chainsaw-handed monster hunter who’s spent the last three decades avoiding maturity, and the terrors of the Evil Dead. But when a Deadite plague threatens to destroy all of mankind, he’s forced to face his demons — both metaphorical and literal.

    Markimdb: 6
    Genrehorror, fantastic, drama
    CountryUSA

    After a mysterious disease begins transforming people into vampires, Dr. Luther Swann is pitted against his best friend, now a powerful vampire leader.

    Markimdb: 8.2
    Genrehorror, thriller, drama
    CountryUSA
    Duration00:43

      Sheriff's deputy Rick Grimes awakens from a coma to find a post-apocalyptic world dominated by flesh-eating zombies. He sets out to find his family and encounters many other survivors along the way.

      Markimdb: 7.7
      Genreaction, thriller, drama
      CountryUSA
      Duration03:06

      Young CIA analyst Joe Turner has his idealism tested when he learns that the CIA has been using an algorithm he developed to spy on American citizens, leading the organization to a terrorist plot that threatens the lives of millions. Inspired by Sydney Pollack’s 1975 political thriller Three Days of the Condor.

      Genredrama
      CountryUSA

      The story of how one company triggered the worst drug epidemic in American history. Look into the epicenter of America's struggle with opioid addiction, from a distressed Virginia mining community, to the hallways of the DEA, and to the opulence of "one percenter" Big Pharma Manhattan.

      Markimdb: 6.8
      Genredrama, crime
      CountryUSA
      Duration00:43

      Gloria Sheppard is an intuitive LAPD homicide detective who juggles her demanding personal and professional lives while raising two sons with the help of her troubled younger brother, Davey.

      Markimdb: 7.7
      Genrecomedy
      CountryUSA

      A single-camera buddy comedy about what happens when two best friends come back together, just when they need each other most. Inspired by the ultra-close friendship between the series' creators and stars, "Playing House" centers on mother to-be Maggie who asks her single and career-driven best friend Emma to return home from her job overseas to attend her baby shower, having no idea what’s truly in store.

      Markimdb: 7.4
      Genrecomedy
      CountryUSA
      Duration00:28

      Stuart Pritchard is an awkward, overly-confident Englishman trying to date in Los Angeles – where he repeatedly attempts to infiltrate the world of beautiful people.

      Markimdb: 8.4
      Genredrama
      CountryUSA
      Duration00:43

      Set in the early 1980s, and about a fictional visionary, an engineer and a prodigy whose innovations confronts the corporate behemoths of the time. Their personal and professional partnership will be challenged by greed and ego while charting the changing culture in Texas' Silicon Prairie.

      Markimdb: 5.6
      Genrecomedy, drama, family
      CountryUSA

      Sam & Cat is an American teen sitcom that premiered June 8, 2013, on Nickelodeon. It is a crossover spin-off/sequel of both iCarly and Victorious. It stars Jennette McCurdy as Sam Puckett and Ariana Grande as Cat Valentine. The girls meet by chance during a bizarre adventure and become roommates, then start a babysitting business to earn extra money.

      Markimdb: 8.5
      Genredocumentary
      CountryUSA

      They're philosophers, storytellers and pioneers in their fields. Four surgeons reflect on their lives and professions in this inspiring docuseries.

      Markimdb: 6.3
      Genrecomedy, melodrama
      CountryUSA

      Six years ago, Annie and Jake bonded over their mutual love of nachos and they've been inseparable ever since. Now, after returning from a romantic two-week island vacation, Jake’s all set to pop the question. Before he can ask, though, Annie lets loose on Jake for his inability to commit. She was expecting him to “put a ring on it” in paradise and now Jake’s perfect proposal is ruined. Not wanting to spend the next 60 years talking about that mess of a proposal, Jake and Annie decide to hold off on the engagement until they can do it right. Yet if history tells us anything, it’s when we really want things to go right that they all tend to go wrong. The only thing we know for sure is these two are destined to be together whether they can get it together or not.

      Markimdb: 7.2
      Genrecomedy
      CountryUSA

      Danny Burton is a 30-ish carefree single guy who has watched most of his friends move on to serious relationships. When his last remaining friend Shannon moves out to get married, Danny searches for a new roommate. A promising candidate is Justin, the owner of Black Eyes Bar in Detroit (frequently mispronounced "Black Guys Bar"). Justin and his friends - the nerdy Burski, oddball Shelly, and recently out-of-the-closet gay guy Brett - all have certain qualities that make them appear "undateable".

      Markimdb: 8.6
      Genredrama, sport
      CountryUSA

      In a Kentucky orphanage in the 1950s, a young girl discovers an astonishing talent for chess while struggling with addiction.

      Markimdb: 6.8
      Genremelodrama, drama
      CountryUSA
      Duration00:59

      Ordinary college student Paige gets her big break after auditioning for the starring role in a Hollywood blockbuster. She must now navigate her new star-studded life and the highs and lows that come with being the new It Girl in town as well as balancing her college workload.

      Markimdb: 6.3
      Genrefantastic, drama, detective
      CountryUSA
      Duration03:56

      When a mysterious object crashes to Earth, a group of seemingly unconnected strangers die from the energy pulse, but then awaken to learn that they have assigned the task of preventing the impending Apocalypse.

      Markimdb: 8.3
      Genredocumentary
      CountryUSA
      Duration01:48

      Step inside the minds of the most innovative designers in a variety of disciplines and learn how design impacts every aspect of life.

      Markimdb: 6.1
      Genrehorror, fantastic, fantasy, drama
      CountryUSA

      An anthology series of stand alone episodes delving into horror myths, legends and lore.

      Markimdb: 7.7
      Genrecomedy
      CountryUSA

      An aspiring actor and his sister Brooke, a former professional dancer, try to find their place in the world while wrestling with their feelings about their 13-year-old brother Chase's sudden rise to internet fame.

      Markimdb: 7.3
      Genrecomedy
      CountryUSA
      Duration00:22

      After a naive Midwestern girl's big city dreams are dashed her first week in New York, she finds herself living with her worst nightmare in this hilarious, contemporary comedy about a female odd couple who are surrounded by an outrageous cast of characters.

      Markimdb: 6.4
      Genredrama, biography, history
      CountryUSA

      A revelatory reframing of American leadership through the lens of the First Ladies. Exploring everything from their journeys to Washington, family life, and world-changing political contributions, the impact of the White House's women is no longer hidden from view.

      Markimdb: 6.3
      Genrefantastic, action, comedy, cartoon
      CountryUSA

      The megalomaniacal supervillain M.O.D.O.K. has long pursued his dream of one day conquering the world. But after years of setbacks and failures fighting the Earth’s mightiest heroes, M.O.D.O.K. has run his evil organization A.I.M. into the ground. Ousted as A.I.M.’s leader, while also dealing with his crumbling marriage and family life, the Mental Organism Designed Only for Killing is set to confront his greatest challenge yet: a midlife crisis!

      Markimdb: 7.9
      Genrecomedy, crime, detective
      CountryUSA
      Duration02:35

      A bright-eyed New York lawyer takes his first big case defending an eccentric poetry professor accused of murdering his wife.

      Markimdb: 6.2
      Genreaction, comedy, family
      CountryUSA

      K.C. Cooper, a high school math whiz and karate black-belt, learns that her parents are spies when they recruit her to join them in the secret government agency, The Organization. While she now has the latest spy gadgets at her disposal, K.C. has a lot to learn about being a spy, including keeping her new gig a secret from her best friend Marisa. Together, K.C. and her parents, Craig and Kira, and her younger siblings, Ernie and Judy (a humanoid robot), try to balance everyday family life while on undercover missions, near and far, to save the world.

      Markimdb: 7.6
      Genrecomedy
      CountryUSA
      Duration05:15

      The early life of child genius Sheldon Cooper, later seen in The Big Bang Theory.

      Markimdb: 8.1
      Genreaction, comedy, drama, adventure, cartoon, crime
      CountryUSA
      Duration00:22

      Black Dynamite is an American animated television series based on the 2009 film of the same name, although the series follows a separate continuity, with some back-references to the film. The series was announced shortly after the release of the film, the 10-minute pilot episode was released on Adult Swim Video on August 8, 2011, and the full series premiered on Cartoon Network's late night programming block, Adult Swim, on July 15, 2012. Michael Jai White, Byron Minns, Tommy Davidson and Kym Whitley reprise their film roles as Black Dynamite, Bullhorn, Cream Corn and Honeybee, respectively.

      Markimdb: 7.4
      Genrehorror, fantastic, thriller, drama, detective
      CountryUSA

      An archivist takes a job restoring damaged videotapes and gets pulled into the vortex of a mystery involving the missing director and a demonic cult.

      Markimdb: 6.4
      Genrecomedy, drama
      CountryUSA
      Duration00:43

      A family of small-time criminals try to go straight after the father is sent to prison.

      Markimdb: 7.1
      Genrecomedy, detective
      CountryUSA

      Flight attendant Cassandra Bowden wakes in her hotel room hungover from the night before in Dubai with a dead body lying next to her. Afraid to call the police, she continues her morning as if nothing happened. In New York, she is met by FBI agents who question her about her recent layover in Dubai. Still unable to piece the night together, she begins to wonder if she could be the killer.

      Markimdb: 6.8
      Genredrama
      CountryUSA

      Five friends learn to deal with the harsh realities of life after college.

      Markimdb: 6.2
      Genreaction, thriller, comedy
      CountryUSA

      Tired of being the comedic sidekick, Kevin Hart gets his wish when a famous director offers him his dream – to be a leading man action star – but there’s a catch: Kevin must first train at the world’s greatest action star school, run by a lunatic.

      Markimdb: 5
      Genrecomedy, drama, family
      CountryUSA

      The story of David Hobbs, who has spent the last decade playing the perfect father on one of TV’s biggest sitcoms. But when the series ends and his wife resumes her own television career, he finds himself cast in his most challenging role to date: handling the day-to-day needs of three kids who've grown accustomed to not having him around. David soon learns that playing a dad on TV is child’s play compared to the real thing.

      Markimdb: 5.6
      Genredrama
      CountryUSA

      A successful defense lawyer at a boutique firm becomes romantically involved with a client who may or may not be guilty of a brutal crime.

      Markimdb: 7.1
      Genredrama
      CountryUSA
      Duration02:10

      The personal and political struggles, setbacks and triumphs of a diverse family of LGBT men and women who helped pioneer one of the last legs of the U.S. Civil Rights movement from its turbulent infancy in the 20th century to the once unfathomable successes of today. The period piece tells the history of the gay rights movement, starting with the Stonewall Riots in 1969.

      Markimdb: 6.7
      Genrefantastic, action, thriller, drama, detective
      CountryUSA

      A group of young adults who met online are mercilessly hunted by a shadowy deep state organization after they come into possession of a near-mythical cult underground graphic novel.

      Markimdb: 7.1
      Genreaction, thriller, drama, adventure, crime
      CountryUSA
      Duration04:12

      A locally born and bred S.W.A.T. lieutenant is torn between loyalty to the streets and duty to his fellow officers when he's tasked to run a highly-trained unit that's the last stop for solving crimes in Los Angeles.

      Markimdb: 6.5
      Genrehorror, thriller, fantasy, drama, detective
      CountryUSA
      Duration01:54

      Consumed by the mystery surrounding the donor heart that saved her life, a young patient starts taking on sinister characteristics of the deceased.

      Markimdb: 8
      Genrefantastic, drama
      CountryUnited Kingdom, USA, Sweden
      Duration01:00

      In a parallel present where the latest must-have gadget for any busy family is a 'Synth' - a highly-developed robotic servant that's so similar to a real human it's transforming the way we live.

      Markimdb: 7.6
      Genrecomedy, crime
      CountryUSA, Canada
      Duration00:46

      Buddy Dobbs, a slacker on the run from a loan shark, steals a man's identity and ends up posing as a small town's new gay pastor.

      Markimdb: 7.8
      Genrecomedy, history
      CountryUSA

      Historical reenactments from A-list talent as told by inebriated storytellers. A unique take on the familiar and less familiar people and events from America’s great past as great moments in history are retold with unforgettable results.




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