20 best movies like Splice (2009)

Martin Brundle, born of the human/fly, is adopted by his father's place of employment (Bartok Inc.) while the employees simply wait for his mutant chromosomes to come out of their dormant state.

Survivors of a nuclear attack are grouped together for days in the basement of their apartment building, where fear and dwindling supplies wear away at their dynamic.

Eccentric scientist Victor Von Frankenstein creates a grotesque creature in an unorthodox scientific experiment.

France, June 1944. On the eve of D-Day, some American paratroopers fall behind enemy lines after their aircraft crashes while on a mission to destroy a radio tower in a small village near the beaches of Normandy. After reaching their target, the surviving paratroopers realise that, in addition to fighting the Nazi troops that patrol the village, they also must fight against something else.

Five medical students, hoping to gain insight into the mystery of what lies beyond the confines of life, embark on a daring and dangerous experiment. By stopping their hearts for short periods of time, each triggers a near-death experience. As the investigation becomes more and more perilous, they are forced to confront the sins of their pasts, as well as contend with the paranormal consequences of trespassing to the other side.

Canadian scientist, Dr Geoff Burton takes up a position at a new institute in wintry Dresden in order to contribute to their most important project—a human regeneration gene—that also has the potential to make something miraculous out of a personal tragedy that has haunted him for years.

A couple agree to have their deceased son cloned under the supervision of an enigmatic doctor, but bizarre things start to happen years after his rebirth.

A loving father finds a clown suit for his son's birthday party, only to realize the suit is part of an evil curse that turns its wearer into a killer.

A group of scientists have developed the Resonator, a machine which allows whoever is within range to see beyond normal perceptible reality. But when the experiment succeeds, they are immediately attacked by terrible life forms.

The widow, Deputy Sheriff Jane Kozik, moves from Manhattan to Black Stone, New York, with her daughter Kelsey Kozik. There she expects to find a safe place to live. The day after moving, a homeless man is found dead in the tool shed of Jane's blind friend Beverly Rowe. Devin Hall and the entomologist Katherine Randell are summoned to help with the investigation. Devin is Jane's brother-in-law and former boyfriend, and Jane still has a crush on him. Meanwhile, Kelsey befriends the scientist Eli Giles, who has developed genetically modified wasps to the army as a weapon, and now he is trying to revert the process. When the wasps attack Black Stone, Jane, Devin and Eli team-up to attempt to destroy the swarm.

In a post-zombie world, where the infected live normal lives, their retroviral drug is running out.

The story of a heartbroken man who attends a spiritual retreat, only to discover that the course releases more than everyday toxins and traumatic experiences.

A documentary filmmaker turns his lens on an enigmatic conspiracy theorist who claims he's found the entrance to a vast underground city populated entirely by monsters.

Ethan is suffering enormous guilt after his parents are killed in a car accident. He quits a promising future at MIT and work on a revolutionary experiment in order to care for his younger siblings.

People disappear every year out in the snow--but this year, something is adding to the body count. Jim and his research team study the Canadian Lynx every year. This year, he has to take his rebelling 16 year-old daughter, Emmy, with him. But the lynx are missing. As Jim and his team try to find why, something stalks them--a predator no prey can escape.

In an alternate reality, Fidel Castro uses genetic engineering to build the new man and thus save utopia. The experiment fails as these beings are highly intelligent but also cruel and uncontrollable. Rejected by their own creators, a group organizes a series of terrorist actions, and chaos reigns on the island. One of its members traces the origin of their genes and begins a journey to try to discover their humanity.

The son of the inventor of a matter-transporter, which turned him into a monster when he tried to transport himself along with a tiny housefly, continues to pursue his father's experiment, while his own two sons attempt to extricate him, themselves and the family name from further disaster and scandal.

A biologist signs up for a dangerous, secret expedition into a mysterious zone where the laws of nature don't apply.

A shipwrecked sailor stumbles upon a mysterious island and is shocked to discover that a brilliant scientist and his lab assistant have found a way to combine human and animal DNA—with horrific results.

With the world under attack by deadly creatures who hunt by sound, a teen and her family seek refuge outside the city and encounter a mysterious cult.

A university research scientist, about to lose funding and status, has a lab accident and discovers he can see people's true intentions -- making his situation even worse.

On a bleak future Earth, a soldier endures a radical genetic transformation to save humanity. But his wife fears he's becoming more creature than man.

Toshiaki Nagashima is a biologist who is doing major research on mitochondria. When his beautiful young wife is tragically involved in a car accident which leaves her brain dead, in desperation he steals her liver from her body in order to recieve the mitochondria from it to resurrect his wife from the dead. The killer mitochondria takes the form of his assistant.

Group of heroin smugglers finds shelter on abandoned oil rig after their ship had exploded. Soon they find that the oil rig was just cover for biological experiment. One of the results is Charlie - shape-shifting monster with ability to absorb the memory of its victims. However, even such creatures have their own bad habits.

Timmy Robinson's best friend in the whole wide world is a six-foot tall rotting zombie named Fido. But when Fido eats the next-door neighbor, Mom and Dad hit the roof, and Timmy has to go to the ends of the earth to keep Fido a part of the family. A boy-and-his-dog movie for grown ups, "Fido" will rip your heart out.

In the future, a strange fungus has changed nearly everyone into a thoughtless, flesh-eating monster. When a scientist and a teacher find a girl who seems to be immune to the fungus, they all begin a journey to save humanity.

Once again tampering with mother nature to disastrous results, Dr. Herbert West continues his research while serving time in a maximum security prison for his previous exploits. West's limited prison-cell experiments are suddenly interrupted by the arrival of a new prison doctor and the brother of the girl who suffered from West's experiments 13 years earlier.

When plans for a weekend vacation hit a dead end, a group of close-knit friends find themselves stranded in unfamiliar territory, pursued by a menacing predator. Holed up in an isolated cabin, tensions mount as long-buried secrets are revealed. As the body count rises, the group must put their differences aside and fight for survival.

Friends on a weekend excursion take a path into a forest that leads to death and destruction.

Three college students on a road trip across the Southwest experience a detour – the tracking of a computer genius who has already hacked into MIT and exposed security faults. When the trio find themselves drawn to an eerily isolated area, suddenly everything goes dark. When one of the students regains consciousness, he finds himself in a waking nightmare.

A genetically engineered plant scatters its seeds and seems to cause uncanny changes on living creatures. The afflicted appear strange, as if they were replaced - especially for those, who are close to them. Or is it all just imagination? Thus starts a play between various truths,on which end stands the loss of the own identity.

It is about two Atheists who run a video blog debunking Psychics, Mediums and religious beliefs. However, a death experiment goes totally wrong and as a result they attract evil entities that stalk and haunt them.

When a group of close-knit friends assemble for the marriage of Skylar and Dan, they have no idea they will witness The Rapture and face a series of catastrophic events turning the celebration into a life-or-death struggle.

Siblings Mimi and Luke unwittingly resurrect an ancient alien overlord. Using a magical amulet, they force the monster to obey their childish whims, and accidentally attract a rogues’ gallery of intergalactic assassins to small-town suburbia.

Juliette, a lone survivor of an apocalyptic era, fights to survive against hunger, thirst, a broken leg and strange disturbing creatures that only comes out at nighttime.

The six-member crew of the International Space Station is tasked with studying a sample from Mars that may be the first proof of extra-terrestrial life, which proves more intelligent than ever expected.

Eight strangers are thrown together by mysterious forces and must help each other survive in a violent world that defies explanation.

Following the events at home, the Abbott family now face the terrors of the outside world. Forced to venture into the unknown, they realize that the creatures that hunt by sound are not the only threats that lurk beyond the sand path.

Already deep into a second Cold War, Britain’s Ministry of Defense seeks a game-changing weapon. Programmer Vincent McCarthy unwittingly provides an answer in The Machine, a super-strong human cyborg. When a programming bug causes the prototype to decimate his lab, McCarthy takes his obsessive efforts underground, far away from inquisitive eyes.

On a remote Irish farm, five people become unwilling participants in an experiment that goes nightmarishly wrong.

Orbiting above a planet on the brink of war, scientists test a device to solve an energy crisis and end up face-to-face with a dark alternate reality.

A group of young Miskatonic University scientists invent a time machine, only to learn that they are being manipulated by mysterious, unseen forces from another dimension.

A lone-wolf scientist sequestered in a mansion near a small desert town arouses the suspicion of the town's doctor when his lab assistant is found dead from a case of acromegaly which took only four days to develop. As the doctor investigates, aided by the scientist's new, and very female, assistant, they discover that, far worse, something much larger and hungrier than it ever should be, is devouring local cattle - and humans - in increasingly large quantities.

A teen faces a night of terror when three malevolent trick-or-treaters come knocking at her door.

From the mind behind Evangelion comes a hit larger than life. When a massive, gilled monster emerges from the deep and tears through the city, the government scrambles to save its citizens. A rag-tag team of volunteers cuts through a web of red tape to uncover the monster's weakness and its mysterious ties to a foreign superpower. But time is not on their side - the greatest catastrophe to ever befall the world is about to evolve right before their very eyes.

A single mom tries to break free from a mysterious organization that has abducted her.

Four boyhood pals perform a heroic act and are changed by the powers they gain in return. Years later, on a hunting trip in the Maine woods, they're overtaken by a vicious blizzard that harbors an ominous presence. Challenged to stop an alien force, the friends must first prevent the slaughter of innocent civilians by a military vigilante ... and then overcome a threat to the bond that unites the four of them.

Carrie White is a lonely and painfully shy teenage girl with telekinetic powers who is slowly pushed to the edge of insanity by frequent bullying from both classmates at her school, and her own religious, but abusive, mother.

When a young ski team training for the Olympics arrives at the remote and isolated Lost Mountain Ski Resort to focus on training, they're thrilled to find a retired Olympic skier is there to help them train. But their plans are halted when a scientist working at a nearby government lab arrives with the horrifying news that a top secret Government project has produced giant spiders and they have escaped, killing and eating everything in sight.

In the wake of the end of the world, a family of four desperately tries to survive. Their goal: escaping the city and traveling to the rural community they once called home. The constant threat of a violent death forcing them to stay as far away from civilization as possible, they take to the forest, soon to discover the danger posed by other survivors may be the least of their worries.