20 best shows like Dr. Brain (2021)

A vast international plot explodes when a beautiful Jane Doe is discovered naked in Times Square, completely covered in mysterious, intricate tattoos with no memory of who she is or how she got there. But there's one tattoo that is impossible to miss: the name of FBI agent Kurt Weller, emblazoned across her back. "Jane," Agent Weller and the rest of the FBI quickly realize that each mark on her body is a crime to solve, leading them closer to the truth about her identity and the mysteries to be revealed.

Anthology series about famous geniuses with the first season charting how Albert Einstein unlocked the mysteries of the atom and the universe, and the second exploring the passionate nature and relentless creative drive of Pablo Picasso.

Follows Lia Haddock, a journalist for American Public Radio (APR), as she unravels the mystery behind the disappearance of over 300 people at a neuroscience research facility in Tennessee.

Prairie Johnson, blind as a child, comes home to the community she grew up in with her sight restored. Some hail her a miracle, others a dangerous mystery, but Prairie won’t talk with the FBI or her parents about the seven years she went missing.

A fresh look at the life and legacy of the iconic artist Leonardo da Vinci, positing that he was a gay outsider who used his work as a way of hiding his true self. Each episode will examine one of da Vinci’s artworks for hidden clues about a tortured artist struggling for perfection.

Love — and lies — spiral when a DNA researcher helps discover a way to find the perfect partner, and creates a bold new matchmaking service.

After landing from a turbulent but routine flight, the crew and passengers of Montego Air Flight 828 discover five years have passed in what seemed like a few hours. As their new realities become clear, a deeper mystery unfolds and some of the returned passengers soon realize they may be meant for something greater than they ever thought possible.

Ten scientists trapped in a mobile science laboratory at the South Pole realize that one among them is a killer.

FBI Special Agent Olivia Dunham, brilliant but formerly institutionalized scientist Walter Bishop and his scheming, reluctant son Peter uncover a deadly mystery involving a series of unbelievable events and realize they may be a part of a larger, more disturbing pattern that blurs the line between science fiction and technology.

A single mother enters a world of twisted mind games when she begins an affair with her psychiatrist boss while secretly befriending his mysterious wife.

Before there was Batman, there was GOTHAM. Everyone knows the name Commissioner Gordon. He is one of the crime world's greatest foes, a man whose reputation is synonymous with law and order. But what is known of Gordon's story and his rise from rookie detective to Police Commissioner? What did it take to navigate the multiple layers of corruption that secretly ruled Gotham City, the spawning ground of the world's most iconic villains? And what circumstances created them – the larger-than-life personas who would become Catwoman, The Penguin, The Riddler, Two-Face and The Joker?

Young computer engineer Lily Chan investigates the secretive development division of her employer, a cutting-edge tech company based in San Francisco, which she believes is behind the murder of her boyfriend.

In the year 2093, a team of scientists aboard the Nightflyer, the most advanced ship ever built, embarks on a journey to find other life forms. Their mission takes them to the edge of the solar system, and to the edge of insanity, as they realize true horror isn't waiting for them in outer space—it's already on their ship.

When a teenage couple runs away to be together, the extraordinary gift they possess unleashes powerful forces intent on dividing them forever.

Each episode transports the audience to worlds of wonder through the lens of today’s most imaginative filmmakers, directors and writers. A reimagining of the original anthology series by Steven Spielberg.

Dollhouse is an American science fiction television series that revolves around a corporation running numerous underground establishments across the globe which program individuals referred to as "Actives" with temporary personalities and skills. Wealthy clients hire Actives from Dollhouses at great expense for various purposes. The series primarily follows the Active known as Echo, played by Eliza Dushku, on her journey towards self-awareness.

After a fortuitous drug bender saves his life, addict Jake ventures out into the quiet streets… unaware that most of the world already died in their beds. Now, battling sleepless fatigue and encroaching delirium, Jake teams with a scrappy teenager, overnight doctor and red-eye pilot to search for answers… and just maybe find a way to sleep again.

Helix is an intense thriller about a team of scientists from the Centers for Disease Control who travel to a high-tech research facility in the Arctic to investigate a possible disease outbreak, only to find themselves pulled into a terrifying life-and-death struggle that holds the key to mankind's salvation...or total annihilation.

Person of Interest follows former CIA paramilitary operative, John Reese, who is presumed dead and teams up with reclusive billionaire Finch to prevent violent crimes in New York City by initiating their own type of justice. With the special training that Reese has had in Covert Operations and Finch's genius software inventing mind, the two are a perfect match for the job that they have to complete. With the help of surveillance equipment, they work "outside the law" and get the right criminal behind bars. 

A missing FBI agent reappears six years after being declared dead.

The provocative story of Cole, a time traveler from a decimated future in a high-stakes race against the clock. Utilizing a dangerous and untested method of time travel, he journeys from 2043 to the present day on a mission to locate and eradicate the source of a deadly plague that will all but annihilate the human race.

Grace and Jonathan Fraser are living the only lives they ever wanted. Overnight a chasm opens in their lives: a violent death and a chain of terrible revelations. Left behind in the wake of a spreading and very public disaster, Grace must dismantle one life and create another for her child and her family.

A post-apocalyptic story about a botched U.S. government experiment that turns a group of death row inmates into highly infectious vampires, and an orphan girl who might be the only person able to stop the ensuing crisis.

When an explosion at a top-secret government lab injures an elderly janitor, no one could have expected the terrifying results. Exposure to mysterious chemicals causes him to undergo a bizarre transformation. He is slowly... incredibly... growing younger every day. Now, a ruthless CIA assassin will stop at nothing to take him prisoner and turn him into a government guinea pig. With his future on the line, the janitor goes on the run with his wife and a feisty female agent. All the while, he continues to transform... into a being with powers that are as deadly as they are unimaginable.

A young woman is recruited into a secret government agency to be “stitched” into the minds of the recently deceased, using their memories to investigate murders.

4400 centers on the return of 4400 people who, previously presumed dead or reported missing, reappear on Earth. Though they have not aged physically, some of them seem to have deeper alterations ranging from superhuman strength to an unexplained healing touch. A government agency is formed to track the 4400 people after one of them commits a murder.

John Doe is an American science fiction drama television series that aired on Fox during the 2002–2003 TV season.

When a young boy vanishes, a small town uncovers a mystery involving secret experiments, terrifying supernatural forces, and one strange little girl.

The Utopia Experiments is a legendary graphic novel shrouded in mystery. When a group of strangers find themselves in possession of an original manuscript, their lives suddenly and brutally implode.

FBI agent Audrey Parker arrives in the small town of Haven, Maine to solve a murder and soon discovers the town's many secrets—which also hold the key to unlocking the mysteries of her lost past.

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A U.S. satellite crash-lands near a small town in Utah, unleashing a deadly plague that kills virtually everyone except two survivors, who may provide clues to immunizing the population. As the military attempts to quarantine the area, a team of highly specialized scientists is assembled to find a cure and stop the spread of the alien pathogen, code-named Andromeda.

Last Resort is an American military drama television series. When the crew of the U.S. Navy Ohio-class ballistic missile submarine, the USS Colorado, pick up a U.S. Navy SEAL team off Pakistan's coast, the Colorado receives an order to launch nuclear ballistic missiles at Pakistan.

To escape reality 17-year-old Leila turns to a secret virtual paradise. Her real journey begins when this digital Eden turns dark.

Tales of science fiction, fantasy and the occult, exploring humanity's hopes, despairs, prides and prejudices in metaphoric ways. Next stop ahead The Twilight Zone.

A chronicle of the true top secret U.S. Air Force-sponsored investigations into UFO-related phenomena in the 1950s and ’60s, known as “Project Blue Book.”

Siberia is an American mockumentary series about a reality television show where 16 contestants must survive in the Siberian territory of Tunguska. The show was filmed in Birds Hill Provincial Park just north of Winnipeg, Manitoba, Canada. It premiered on NBC on July 1, 2013. The first season was met with generally favorable reviews from critics and viewers, with average viewership per episode coming in around 2.03 million viewers. Metacritic scored the show with a 63 out of 100. The series concluded its first season on September 16, 2013.

After a massive alien artifact lands on Earth, Niko Breckinridge leads an interstellar mission to track down its source and make first contact.

It is a long told story about underground of Istanbul streets.

The black sheep of the Argyll family, Jack Argyll, was accused of murdering their matriarch a year ago, but now a man shows up on their doorstep claiming Jack’s innocence. The family must come to terms with this news and the fact that the real killer might still be among them.

A genetics professor experiments with a treatment for his comatose sister that blends medical and shamanic cures, but unlocks a shocking side effect.

An English teacher travels back in time to prevent the Kennedy assassination, but discovers he is attached to the life he has made in a bygone era.

A North American spin-off of the hit U.K. television series, Primeval: New World follows a specialized team of animal experts and scientists that investigates the appearance of temporal anomalies and battles both prehistoric and futuristic creatures.

A wary CIA officer investigates a charismatic man who sparks a spiritual movement and stirs political unrest. Who exactly is he? And what does he want?

Set in a single room of an average American motel, each episode tells a different story of the assorted characters who pass through it.

Four young friends' paper routes are disrupted on Hell Day 1988, when they unknowingly time travel to 2019. While searching for a way home, they come face-to-face with their adult selves and learn how to work together to save the world.

Dr. Daniel Pierce, a neuroscientist and professor, is recruited to help the federal government crack difficult cases. His intimate knowledge of human behavior and masterful understanding of the mind give him an extraordinary ability to read people, but his eccentric view of the world and less-than-stellar social skills can often interfere with his work.

We love to play games with our children. But what happens when someone else starts to play with them too? Someone we don't know. Can't see. Can't hear. In The Whispers, someone or something -- is manipulating the ones we love most to accomplish the unthinkable. An unseen alien force has figured this human weakness out. They have invaded earth and are using our most unlikely resource to achieve world domination – our children.

After a brutal virus wipes out most of the population, two young siblings embark on a perilous search for safety. A Scandinavian thriller series.

Set amidst a wave of violent animal attacks sweeping across the planet, a young renegade scientist is thrust into a race to unlock the mystery behind this pandemic before time runs out for animals and humans alike.