American movies about epidemics and viruses

List of the best American movies about epidemics and virus infection, selected by visitors to our site.: Contagion, Locked Down, Only, Tape 407, Containment, Blood Red Sky, The Invasion, Cabin Fever, Toxin, Kingsman: The Golden Circle.

In the top there are new films of 2022, a plot description and trailers for films that have already been released.

Country
Markimdb: 6.7
Genreaction, thriller, drama
CountryUSA, United Arab Emirates
Duration01:46

As an epidemic of a lethal airborne virus - that kills within days - rapidly grows, the worldwide medical community races to find a cure and control the panic that spreads faster than the virus itself.

Markimdb: 5.2
Genrecomedy, melodrama, crime
CountryUnited Kingdom, USA

During a COVID-19 lockdown, sparring couple Linda and Paxton call a truce to attempt a high-risk jewellery heist at one of the world's most exclusive department stores, Harrods.

Markimdb: 5
Genrefantastic, melodrama, drama
CountryUSA

After a comet releases a mysterious virus that begins to kill all of the women in the world, a young couple's relationship is severely tested. They hide out (from both the illness and the savages who hunt the remaining women) in their over-sterilized apartment. Ultimately the duo escapes their self-imposed quarantine to head to the wilderness.

Markimdb: 3.5
Genrehorror, fantastic, thriller
CountryUSA

Survivors of an airplane crash find themselves within the borders of a government testing area and pursued by predators.

Markimdb: 7.1
Genredrama
CountryUSA
Duration03:31

An epidemic breaks out in Atlanta leaving the large city quarantined and those stuck on the inside fighting for their lives. This is the story of loved ones torn apart, and how the society that grows inside the quarantine reveals both the devolution of humanity and the birth of unlikely heroes.

Markimdb: 6.1
Genrehorror, action, thriller
CountryGermany, USA

A woman with a mysterious illness is forced into action when a group of terrorists attempt to hijack a transatlantic overnight flight. In order to protect her son she will have to reveal a dark secret, and unleash the inner monster she has fought to hide.

Markimdb: 5.9
Genrefantastic, thriller
CountryUSA, Australia
Duration01:39

    Washington, D.C. psychologist Carol Bennell and her colleague Dr. Ben Driscoll are the only two people on Earth who are aware of an epidemic running rampant through the city. They discover an alien virus aboard a crashed space shuttle that transforms anyone who comes into contact with it into unfeeling drones while they sleep. Carol realizes her son holds the key to stopping the spread of the plague and she races to find him before it is too late.

    Markimdb: 3.7
    Genrehorror, fantastic, thriller
    CountryUSA
    Duration01:52

    In this grisly remake of the 2002 horror hit, five college chums rent an isolated woodland cabin for a party. But their fun quickly ends when the group is exposed to a hideous flesh-eating virus, and survival becomes the name of the game.

    Markimdb: 2.8
    Genrehorror, fantastic, thriller, drama
    CountryUSA
    Duration02:05

    A pharmaceutical company recruits a well-known scientist to help develop a vaccine against a deadly virus.

    Markimdb: 6.7
    Genreaction, thriller, comedy, adventure, crime
    CountryUnited Kingdom, USA
    Duration01:47

    When an attack on the Kingsman headquarters takes place and a new villain rises, Eggsy and Merlin are forced to work together with the American agency known as the Statesman to save the world.

    Markimdb: 3.8
    Genrehorror, fantastic, action, thriller, drama, adventure
    CountryUSA
    Duration01:34

    When zombies overrun San Francisco, a desperate group survives by locking themselves inside Alcatraz Prison. When the undead breach the island, our heros are forced to return to the mainland overrun with the undead.

    Markimdb: 4.3
    Genrehorror, fantastic, thriller, drama, detective
    CountryUSA
    Duration01:28

    When a group of close-knit friends assemble for the marriage of Skylar and Dan, they have no idea they will witness The Rapture and face a series of catastrophic events turning the celebration into a life-or-death struggle.

    Markimdb: 6
    Genredrama, biography, history
    CountryUSA
    Duration01:35

    At an isolated log cabin in the harsh wilderness of Indiana circa 1817, the rhythms of love, tragedy, and the daily hardships of life on the developing frontier shaped one of our nation’s greatest heroes: Abraham Lincoln. Abe is a thoughtful and quiet boy who spends his days at the side of his beloved mother while learning to work the land from his stern father. When illness takes his mother, Abe's new guardian angel comes in the form of his new stepmother, who sees the potential in the boy and pushes for his further education.

    Markimdb: 3.8
    Genrehorror, action, cartoon
    CountryUSA
    Duration01:47

    A group of survivors trapped in a New York apartment fight to stay alive against legions of zombies.

    Markimdb: 4.3
    Genrefantastic, melodrama, drama
    CountryUSA
    Duration01:39

    The interwoven stories of three couples which are forced to make life altering decisions in the face of a disastrous war. Inspired and sometimes blinded by their love, Len, Mia, Andy, Esther, Anna and Erik are as flawed and beautiful as any of the billions who are facing this human-made biological disaster.

    Markimdb: 7
    Genrehorror, fantastic, action, adventure
    CountryUSA
    Duration01:56

      Life for former United Nations investigator Gerry Lane and his family seems content. Suddenly, the world is plagued by a mysterious infection turning whole human populations into rampaging mindless zombies. After barely escaping the chaos, Lane is persuaded to go on a mission to investigate this disease. What follows is a perilous trek around the world where Lane must brave horrific dangers and long odds to find answers before human civilization falls.

      Markimdb: 2.9
      Genrethriller
      CountryUSA
      Duration02:00

      An innocent woman, Claire Scully is drawn into a terrorist plot to kill people through the mail using a deadly strain of TB.

      Markimdb: 5.7
      Genrethriller, drama
      CountryUSA, India, France
      Duration01:46

        An entry-level employee at a powerful corporation finds himself occupying a corner office, but at a dangerous price: he must spy on his boss's old mentor to secure for him a multi-billion dollar advantage.

        Markimdb: 7.9
        Genredrama, adventure, family, biography, history
        CountryUSA

        The untold true story set in the winter of 1925 that takes you across the treacherous terrain of the Alaskan tundra for an exhilarating and uplifting adventure that will test the strength, courage and determination of one man, Leonhard Seppala, and his lead sled dog, Togo.

        Markimdb: 5.4
        Genrehorror, fantastic, action, fantasy
        CountryUSA
        Duration03:58

        Years after a mysterious plague has devastated the planet and turned most of humanity into blood-hungry creatures, a rogue drifter on a vengeful hunt stumbles across a band of survivors in an abandoned police station and reluctantly agrees to try to help them defend themselves and escape to the sanctuary they so desperately need.

        Markimdb: 4.4
        Genrehorror, fantastic, action, thriller, drama
        CountryUSA
        Duration02:09

        When a strange signal pulsates through all cell phone networks worldwide, it starts a murderous epidemic of epic proportions when users become bloodthirsty creatures, and a group of people in New England are among the survivors to deal with the ensuing chaos after.

        Markimdb: 4.9
        Genrefantastic, thriller, adventure
        CountryGermany, South Africa, USA
        Duration01:30

        A group of post-apocalyptic survivors, struggle to survive in a world where jungles and forests and primeval wetlands and deserts have obliterated civilization. They staunchly face genetically mutating beasts and mysterious diseases in an attempt to re-establish the human race as masters of Earth.

        Markimdb: 5
        Genrehorror
        CountryUSA
        Duration00:44

        Picking up directly where the previous film left off, the story follows Riley, one of the last people to come in contact with Samantha, as he scrambles to track down those responsible for the outbreak before the highly contagious disease not only consumes his body, but the world as we know it.

        Markimdb: 4.1
        Genrethriller, drama
        CountryUSA

        Deep in the throes of a global pandemic, up and coming TV star, Ava Boone, is forced to flee the mounting chaos in Los Angeles and return to her rural hometown. But as she struggles to acclimate to a way of life she left behind long ago, her homecoming attracts a dangerous figure from her past – threatening both her and the family that serves as her only sanctuary.

        Markimdb: 4.7
        Genrethriller, drama
        CountryUSA

        After the loss of her family, a young woman struggles to survive in a world long-since destroyed by disease; but when a lonely traveler offers her a place in his community, she must decide if the promise of a better life is worth the risk of trusting him.

        Markimdb: 3.3
        Genrehorror, fantastic, action, thriller, comedy, adventure
        CountryUSA

        When a strange virus quickly spreads through a safari park and turns all the zoo animals undead, those left in the park must stop the creatures before they escape and zombify the whole city.

        Markimdb: 5.5
        Genrefantastic, thriller, drama
        CountryUSA

        After a deadly virus wipes out most of humanity, the survivors are forced to wait alone in self-sustaining bunkers while the viral threat runs its course. Able to communicate through a networked video interface, the survivors wait for years and slowly become a motley family of sorts. But their fragile social ecosystem is shattered when, one by one, they start mysteriously disappearing from their bunkers.

        Markimdb: 6.5
        Genrehorror, thriller, detective
        CountryUSA, United Arab Emirates
        Duration01:37

        Four friends find themselves trapped in their small hometown after they discover their friends and neighbors going quickly and horrifically insane.

        Markimdb: 5.7
        Genrehorror, action, drama
        CountryUSA

        Following a zombie outbreak in Las Vegas, a group of mercenaries take the ultimate gamble: venturing into the quarantine zone to pull off the greatest heist ever attempted.

        Markimdb: 4.4
        Genrehorror, thriller
        CountryUSA
        Duration01:45

        A wild animal attacks six medical students on a weekend hike in the woods. One by one, they become infected with a “feral disease,” turning them into rabid, bloodthirsty creatures, and the vacation becomes a nightmare as they fight to survive each other.

        Markimdb: 5
        Genrecartoon
        CountryUSA

        Get ready to power up! When Barbie magically gets pulled into her favorite video game, she is excited to see she's transformed into a fun roller-skating character. In the game, she meets Cutie, the lovable cloud-shaped friend, and Bella, the roller-skating princess. Together, they soon discover a mischievous emoji is trying to take control of the game. As they travel from level to level, Barbie must rely on her amazing gaming skills and out-of-the box thinking to save her team and beat the game!

        Markimdb: 6.7
        Genrehorror, action, comedy
        CountryUSA
        Duration02:23

        Columbus, Tallahassee, Wichita, and Little Rock move to the American heartland as they face off against evolved zombies, fellow survivors, and the growing pains of the snarky makeshift family.

        Markimdb: 5.5
        Genrehorror, comedy, melodrama
        CountryUSA
        Duration01:39

        After a one night stand Deb wakes up in the middle of a zombie apocalypse.

        Markimdb: 5.2
        Genrehorror, fantastic, thriller
        CountryUSA
        Duration01:30

        Chaos consumes a small town when a chemical facility explodes releasing a deadly toxin. Moments after the leak, the town's residents show signs of mutation, causing the military to quarantine the area leaving any survivors helpless and trapped inside. The story follows Jim, a young man isolated within the red zone, as he eludes flesh eating zombies in an attempt to win back his freedom.

        Markimdb: 6.2
        Genreaction, thriller, comedy, adventure, crime
        CountryUnited Kingdom, USA
        Duration02:18

        Wrongfully accused and on the run, a top MI6 assassin joins forces with his long-lost, football hooligan brother to save the world from a sinister plot.

        Markimdb: 7.2
        Genrethriller, drama, crime, film noir
        CountryUSA
        Duration01:36

        One night in the New Orleans slums, vicious hoodlum Blackie and his friends kill an illegal immigrant who won too much in a card game. Next morning, Dr. Clint Reed of the Public Health Service confirms the dead man had pneumonic plague. To prevent a catastrophic epidemic, Clint must find and inoculate the killers and their associates, with the reluctant aid of police captain Tom Warren, despite official skepticism, and in total secrecy, lest panic empty the city. Can a doctor turn detective? He has 48 hours to try...

        Markimdb: 4
        Genrehorror, fantastic, action, thriller, adventure
        CountryUnited Kingdom, USA
        Duration01:26

        Months after a zombie plague has wiped out 90 percent of the American population, a small group of survivors fight their way cross-country to a rumored refuge on the island of Catalina.

        Markimdb: 2.4
        Genrehorror, fantastic, action, military
        CountryCanada, Italy, USA, Germany
        Duration01:30

        A bacteriological weapon developed by the US Government to create a super soldier - spreads an epidemic in a quiet little town in the middle of Eastern Europe. All citizens have been turned into infected zombies. The plan is to bring an atomic bomb into the city's nuclear plant to pretend a terrible accident occurred. No one has to know the truth. A team of mercenaries is hired to complete the mission. The battle is on. Hordes of monsters against the team. Who will survive?

        Markimdb: 3.3
        Genrefantastic, thriller, drama
        CountryUSA

        A slow-paced, action thriller about a virus that strikes a New Mexico county and the local veterinarian who gets caught in the middle.

        Markimdb: 5.2
        Genrehorror, fantastic, action
        CountryUSA
        Duration02:04

        Based on the game, Dead Rising takes place during a large-scale zombie outbreak. When a mandatory government vaccine fails to stop the infection from spreading, the four leads must evade infection while also pursuing the root of the epidemic, with all signs pointing to a government conspiracy.

        Markimdb: 5
        Genrehorror
        CountrySpain, USA, Mexico

        A group of people have just signed up to be camp Councillors at a foreign country. They expect the camp to be the place for a memorable summer. Instead, something strange is going on and some of the campers begin to act strange. Things go terribly wrong real fast as a terrible game of tag has the campers running for their lives or going after the campers.

        Markimdb: 4.6
        Genrehorror, fantastic
        CountryUSA

        In 1989, a breakthrough in "advanced parasitic research" on Cuttyhunk Island gave scientists a jump in human evolution. Initial tests proved promising, as subjects experienced heightened physical and mental strength and awareness. But - something in the experiment went horribly wrong, and the island mysteriously lost three quarters of its population.

        Markimdb: 3.5
        Genrefantastic, action, thriller
        CountryUSA

        A year and a half after the fall of civilization due to a viral outbreak, a former FBI agent is forced to protect a young woman immune to the disease from a dangerous gang leader hunting her.

        Markimdb: 5.7
        Genrehorror, fantastic, comedy
        CountryUSA, Russia
        Duration01:28

        A mysterious virus hits an isolated elementary school, transforming the kids into a feral swarm of mass savages. An unlikely hero must lead a motley band of teachers in the fight of their lives.

        Markimdb: 3.5
        Genrehorror, action, comedy
        CountryUSA
        Duration01:33

        Zombie Hunter is set in a post-apocalyptic Zombie wasteland caused by the mysterious street drug "Natas". We follow one man who has nothing left other than a beat up Camaro and a trunk full of guns and booze. He runs down Flesh Eaters, hunting for sport and redemption, while also running from his past. After crashing into a small group of survivors, who are running low on resources, he decides to lend a hand. But a surprise attack by the Flesh Eaters forces them on the run and puts the Hunter's skills to the test.

        Markimdb: 5.2
        Genrehorror, fantastic, thriller
        CountryUSA, Spain
        Duration01:26

        A plane is taken over by a mysterious virus. When the plane lands it is placed under quarantine. Now a group of survivors must band together to survive the quarantine.

        Markimdb: 5.4
        Genrehorror, fantastic, action, thriller
        CountryUSA, Germany, Canada
        Duration01:36

          The Umbrella Corporation’s deadly T-virus continues to ravage the Earth, transforming the global population into legions of the flesh eating Undead. The human race’s last and only hope, Alice, awakens in the heart of Umbrella’s most clandestine operations facility and unveils more of her mysterious past as she delves further into the complex. Without a safe haven, Alice continues to hunt those responsible for the outbreak; a chase that takes her from Tokyo to New York, Washington, D.C. and Moscow, culminating in a mind-blowing revelation that will force her to rethink everything that she once thought to be true. Aided by new found allies and familiar friends, Alice must fight to survive long enough to escape a hostile world on the brink of oblivion. The countdown has begun.

          Markimdb: 4.9
          Genrehorror, fantastic, thriller
          CountryUSA

          An obsessive doctor working on a cure for AIDS unwittingly creates an aggressive new bacteria that deteriorates the body and enrages the mind.

          Markimdb: 5.5
          Genrehorror, fantastic, drama
          CountryUSA
          Duration02:35

          Following the outbreak of a virus that wipes out the majority of the human population, a young woman documents her family's new life in quarantine and tries to protect her infected sister.

          Markimdb: 6.8
          Genrehorror, comedy, melodrama
          CountryUSA, Canada
          Duration01:38

            After a zombie becomes involved with the girlfriend of one of his victims, their romance sets in motion a sequence of events that might transform the entire lifeless world.




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